Daily clinical reasoning series

November 2025

30 case-based clinical reasoning analyses assigned to the daily casebook sequence for November 2025.

Case-series dates · November 1, 2025 to November 30, 2025

Read Recurrent Hypoglycemia, Frailty, and Treatment Simplification
JT-CR-032 · Diabetes and metabolic health

Series

Recurrent Hypoglycemia, Frailty, and Treatment Simplification

An original case on confirming recurrent hypoglycemia, frailty, kidney change, individualized goals, treatment simplification, devices, and home safety.

hypoglycemiafrailtyolder adults
Read A Young Adult Cancer Survivor Reconnecting With Primary Care
JT-CR-033 · Cancer, blood, infection, and immunity

Series

A Young Adult Cancer Survivor Reconnecting With Primary Care

An original case on rebuilding a cancer treatment summary, evaluating symptoms, risk-based surveillance, fertility, prevention, and care ownership.

cancer survivorshipyoung adultsprimary care
Read Adolescent Chronic Pain and School Reintegration
JT-CR-034 · Children and adolescent health

Series

Adolescent Chronic Pain and School Reintegration

An original case on chronic pain, diagnostic reassessment, function-centered rehabilitation, mental-health safety, medicines, and school return.

adolescent chronic painrehabilitationschool attendance
Read A Child's Hearing Concern and Learning Access
JT-CR-035 · Children and adolescent health

Series

A Child's Hearing Concern and Learning Access

An original case on hearing-screen follow-up, diagnostic audiology, ear disease, language and learning assessment, communication access, and school support.

pediatric hearingaudiologyschool screening
Read Postpartum Hypertension Across the Care Transition
JT-CR-036 · Reproductive and postpartum care

Series

Postpartum Hypertension Across the Care Transition

An original case on postpartum hypertension triage, preeclampsia, home measurement, treatment safety, feeding goals, and primary-care transition.

postpartum hypertensionpreeclampsiahome blood pressure
Read Persistent Fatigue, Weight Change, and When Telehealth Is Not Enough
JT-CR-037 · Prevention, rural health, and care systems

Series

Persistent Fatigue, Weight Change, and When Telehealth Is Not Enough

An original case on diagnostic reset, verified weight change, targeted testing, telehealth limits, Graves disease, and closed-loop follow-up.

persistent fatigueunintentional weight losstelehealth
Read Recurrent Abdominal Pain and School Absence in a Child
JT-CR-038 · Children and adolescent health

Series

Recurrent Abdominal Pain and School Absence in a Child

An original pediatric case on abdominal pain, targeted evaluation, constipation, gut-brain care, school access, and functional recovery.

recurrent abdominal painpediatric gastroenterologyfunctional abdominal pain
Read Migraine, Hypertension, and Contraceptive Choice
JT-CR-039 · Brain and neurologic health

Series

Migraine, Hypertension, and Contraceptive Choice

An original case on migraine aura, blood-pressure confirmation, contraceptive eligibility, reproductive autonomy, and follow-up.

migraine with aurahypertensioncontraception
Read New Atrial Fibrillation With Dyspnea and Volume Overload
JT-CR-040 · Heart and vascular care

Series

New Atrial Fibrillation With Dyspnea and Volume Overload

An original inpatient case on new atrial fibrillation, acute congestion, hemodynamic assessment, rate and rhythm decisions, stroke prevention, and longitudinal heart failure care.

atrial fibrillationacute heart failuredyspnea
Read Severe Hyponatremia After a Medication Change
JT-CR-041 · Kidney, electrolytes, and digestive health

Series

Severe Hyponatremia After a Medication Change

An original inpatient case on symptomatic hypotonic hyponatremia, thiazide exposure, diagnostic classification, controlled correction, water diuresis, and prevention of recurrence.

hyponatremiathiazide diureticelectrolyte emergency
Read Melena, Orthostasis, and Antithrombotic Tradeoffs
JT-CR-042 · Kidney, electrolytes, and digestive health

Series

Melena, Orthostasis, and Antithrombotic Tradeoffs

An original inpatient case on upper gastrointestinal bleeding, hemodynamic resuscitation, endoscopic hemostasis, anticoagulant interruption, antiplatelet necessity, and safe restart decisions.

melenaupper gastrointestinal bleedingorthostasis
Read Sudden Severe Headache With a Normal Neurologic Examination
JT-CR-043 · Emergency and acute care

Series

Sudden Severe Headache With a Normal Neurologic Examination

An original emergency case on thunderclap headache, time-sensitive subarachnoid hemorrhage evaluation, test sequencing, and diagnostic safety after a normal neurologic examination.

thunderclap headachesubarachnoid hemorrhageacute headache
Read Pleuritic Chest Pain and Breathlessness After Immobilization
JT-CR-044 · Emergency and acute care

Series

Pleuritic Chest Pain and Breathlessness After Immobilization

An original emergency case on pulmonary embolism probability, D-dimer and imaging choices, early severity assessment, anticoagulation, disposition, and follow-up.

pulmonary embolismvenous thromboembolismpleuritic chest pain
Read Rapidly Progressive Hives, Wheeze, and Lightheadedness After a Meal
JT-CR-045 · Emergency and acute care

Series

Rapidly Progressive Hives, Wheeze, and Lightheadedness After a Meal

An original emergency case on recognizing and treating food-triggered anaphylaxis, distinguishing adjuncts from first-line care, risk-based observation, trigger evaluation, and recurrence prevention.

anaphylaxisfood allergyepinephrine
Read Acute Low-Back Pain With Saddle Numbness and Urinary Difficulty
JT-CR-046 · Musculoskeletal, sports, and rehabilitation

Series

Acute Low-Back Pain With Saddle Numbness and Urinary Difficulty

An original emergency case on recognizing possible cauda equina syndrome, examining lower sacral function, obtaining emergency MRI, and coordinating spinal decompression and rehabilitation.

acute low-back paincauda equina syndromesaddle numbness
Read Progressive Shin Pain and Low Energy Availability in a Distance Runner
JT-CR-047 · Musculoskeletal, sports, and rehabilitation

Series

Progressive Shin Pain and Low Energy Availability in a Distance Runner

An original sports-medicine case on tibial bone stress injury, imaging after normal radiographs, low energy availability, menstrual and bone health, and criteria-based return to running.

shin paintibial bone stress injurystress fracture
Read Persistent Shoulder Pain and Weakness After a Fall
JT-CR-048 · Musculoskeletal, sports, and rehabilitation

Series

Persistent Shoulder Pain and Weakness After a Fall

An original musculoskeletal case on persistent weakness after shoulder trauma, occult injury, acute-on-degenerative rotator cuff tears, appropriate imaging, treatment choices, and return to work.

shoulder painrotator cuff teartraumatic shoulder injury
Read Severe Hypertension Without Obvious Acute Organ Injury
JT-CR-049 · Heart and vascular care

Series

Severe Hypertension Without Obvious Acute Organ Injury

An original primary-care case on confirming a very high blood pressure, separating hypertensive emergency from severe hypertension without acute organ injury, and building accountable outpatient treatment.

severe hypertensionhypertensive emergencyhome blood pressure
Read Fever, Flank Pain, and Complicated Urinary Infection With CKD
JT-CR-050 · Kidney, electrolytes, and digestive health

Series

Fever, Flank Pain, and Complicated Urinary Infection With CKD

An original case on recognizing pyelonephritis with systemic illness, separating infection from asymptomatic bacteriuria, evaluating obstruction, and choosing kidney-aware culture-directed treatment.

pyelonephritiscomplicated urinary tract infectionchronic kidney disease
Read Worsening Breathlessness in COPD: Exacerbation or Another Emergency?
JT-CR-051 · Lung and sleep health

Series

Worsening Breathlessness in COPD: Exacerbation or Another Emergency?

An original case on acute COPD worsening, controlled oxygen, respiratory failure assessment, and distinguishing pneumonia, pulmonary embolism, and heart failure before discharge.

COPD exacerbationpneumoniarespiratory failure
Read Transient Unilateral Weakness: TIA, Minor Stroke, or Mimic?
JT-CR-052 · Men's health and urology

Series

Transient Unilateral Weakness: TIA, Minor Stroke, or Mimic?

An original emergency case on resolved focal neurologic symptoms, urgent brain and vascular imaging, early recurrence prevention, and distinguishing TIA from minor ischemic stroke and mimics.

transient ischemic attackminor ischemic strokeunilateral weakness
Read Heavy Irregular Uterine Bleeding With Anemia and Anticoagulant Use
JT-CR-053 · Reproductive and postpartum care

Series

Heavy Irregular Uterine Bleeding With Anemia and Anticoagulant Use

An original case on acute and chronic abnormal uterine bleeding, iron-deficiency anemia, endometrial-risk assessment, structural disease, and anticoagulant tradeoffs.

abnormal uterine bleedingheavy menstrual bleedingiron deficiency anemia
Read Painful Expanding Leg Redness in a Person With Diabetes
JT-CR-054 · Eye, skin, and digital safety

Series

Painful Expanding Leg Redness in a Person With Diabetes

An original case on distinguishing cellulitis from abscess, venous thrombosis, stasis inflammation, Charcot change, osteomyelitis, and necrotizing infection while preserving limb and antibiotic safety.

cellulitisdiabetesdiabetic foot
Read Fever, Headache, and Neck Stiffness in an Adult
JT-CR-055 · Men's health and urology

Series

Fever, Headache, and Neck Stiffness in an Adult

Rapidly distinguishes meningitis threats, imaging needs, lumbar puncture timing, and treatment priorities without delaying stabilization.

meningitislumbar punctureempiric therapy
Read Exertional Syncope With a Family History of Sudden Death
JT-CR-056 · Brain and neurologic health

Series

Exertional Syncope With a Family History of Sudden Death

Interprets exertional fainting, inherited cardiac risk, structural disease, and the limits of a normal resting electrocardiogram.

syncopesudden deathcardiomyopathy
Read Incidentally Elevated Liver Enzymes at a Preventive Visit
JT-CR-057 · Mental, behavioral, and substance-use health

Series

Incidentally Elevated Liver Enzymes at a Preventive Visit

Builds a longitudinal evaluation of liver-test patterns, metabolic risk, alcohol, viral hepatitis, medicines, and fibrosis.

liver enzymessteatotic liver diseaseviral hepatitis
Read Poor Weight Gain and Feeding Fatigue in an Infant
JT-CR-058 · Children and adolescent health

Series

Poor Weight Gain and Feeding Fatigue in an Infant

Integrates growth trajectory, observed feeding, cardiac and respiratory clues, safeguarding, and family resource constraints.

growth falteringinfant feedingcongenital heart disease
Read Severe Hyperglycemia Without Ketosis: Crisis Assessment
JT-CR-059 · Diabetes and metabolic health

Series

Severe Hyperglycemia Without Ketosis: Crisis Assessment

Distinguishes hyperosmolar crisis from uncomplicated hyperglycemia while controlling fluid, electrolyte, insulin, and osmolality hazards.

hyperosmolar statehyperglycemiafluid resuscitation
Read A Dermatomal Rash in an Immunocompromised Adult
JT-CR-060 · Men's health and urology

Series

A Dermatomal Rash in an Immunocompromised Adult

Recognizes localized and disseminated zoster, ocular and neurologic complications, and infection-control needs in immunocompromise.

herpes zosterimmunocompromisedissemination
Read A First Seizure in an Adult
JT-CR-061 · Men's health and urology

Series

A First Seizure in an Adult

Separates provoked seizure, epilepsy risk, and mimics while coordinating imaging, toxic-metabolic evaluation, and safety restrictions.

first seizureprovoked seizureelectroencephalography