Daily clinical reasoning series

May 2026

31 case-based clinical reasoning analyses assigned to the daily casebook sequence for May 2026.

Case-series dates · May 1, 2026 to May 31, 2026

Read Head Trauma While Taking an Anticoagulant
JT-CR-213 · Men's health and urology

Series

Head Trauma While Taking an Anticoagulant

Balances urgent CT, neurologic observation, reversal decisions, delayed bleeding risk, anticoagulant interruption, and safe discharge.

head injuryanticoagulationintracranial hemorrhage
Read Breathlessness Years After Anthracycline Treatment
JT-CR-214 · Cancer, blood, infection, and immunity

Series

Breathlessness Years After Anthracycline Treatment

Connects remote anthracycline exposure to late cardiac dysfunction while testing ischemic, valvular, pulmonary, thrombotic, and cancer causes.

anthracyclinecardiomyopathycancer survivorship
Read Smoking Cessation and Lung-Cancer Screening in COPD
JT-CR-215 · Cancer, blood, infection, and immunity

Series

Smoking Cessation and Lung-Cancer Screening in COPD

Combines evidence based tobacco treatment with eligibility, shared decisions, annual completion, and incidental finding follow-up for low dose CT.

COPDsmoking cessationlung cancer screening
Read Unexplained Bruising in a Child
JT-CR-216 · Children and adolescent health

Series

Unexplained Bruising in a Child

Evaluates bruise pattern, development, trauma history, bleeding disorders, occult injury, and child safety without premature attribution.

pediatric bruisingbleeding disorderchild physical abuse
Read Early Satiety and Vomiting in Diabetes
JT-CR-217 · Diabetes and metabolic health

Series

Early Satiety and Vomiting in Diabetes

Confirms delayed gastric emptying only after excluding obstruction and addresses nutrition, glucose variability, medicines, and prokinetic risks.

gastroparesisdiabetesearly satiety
Read Expanding Erythema With Facial Weakness
JT-CR-218 · Men's health and urology

Series

Expanding Erythema With Facial Weakness

Recognizes early disseminated Lyme disease, localizes facial palsy, checks meningitic and cardiac involvement, and selects evidence based testing.

Lyme diseaseerythema migransfacial nerve palsy
Read Back Pain and New Leg Weakness in a Person With Cancer
JT-CR-219 · Men's health and urology

Series

Back Pain and New Leg Weakness in a Person With Cancer

Treats new weakness with cancer-related back pain as metastatic spinal cord compression until urgent MRI and expert review define anatomy.

spinal cord compressionspinal metastasescancer
Read Breast Pain and Fever During Lactation
JT-CR-220 · Reproductive and postpartum care

Series

Breast Pain and Fever During Lactation

A lactation-focused analysis of inflammatory mastitis, bacterial infection, abscess risk, milk drainage, antibiotics, and follow-up.

lactational mastitisbreastfeedingbreast abscess
Read Shoulder and Hip Stiffness With Systemic Symptoms
JT-CR-221 · Eye, skin, and digital safety

Series

Shoulder and Hip Stiffness With Systemic Symptoms

Diagnostic calibration for polymyalgia rheumatica, giant cell arteritis, inflammatory mimics, steroid response, and relapse monitoring.

polymyalgia rheumaticagiant cell arteritismorning stiffness
Read Self-Harm Thoughts After Starting an Antidepressant
JT-CR-222 · Mental, behavioral, and substance-use health

Series

Self-Harm Thoughts After Starting an Antidepressant

Urgent assessment of new self-harm thoughts after antidepressant initiation, including intent, activation, bipolarity, means safety, and follow-up.

suicidal ideationantidepressantsakathisia
Read An Incidental Renal Mass
JT-CR-223 · Men's health and urology

Series

An Incidental Renal Mass

A renal mass analysis covering image characterization, malignancy risk, biopsy limits, surveillance, nephron preservation, and result ownership.

renal massincidental findingBosniak classification
Read Suspected Celiac Disease After Starting a Gluten-Free Diet
JT-CR-224 · Kidney, electrolytes, and digestive health

Series

Suspected Celiac Disease After Starting a Gluten-Free Diet

A celiac diagnosis analysis after gluten restriction, covering serology limits, gluten challenge, biopsy, nutritional injury, and access barriers.

celiac diseasegluten-free diettissue transglutaminase
Read Recurrent Nosebleeds While Taking Anticoagulation
JT-CR-225 · Cancer, blood, infection, and immunity

Series

Recurrent Nosebleeds While Taking Anticoagulation

Management of recurrent epistaxis during anticoagulation, balancing airway and hemorrhage control against thrombosis and reversal harms.

epistaxisanticoagulationnasal packing
Read Syncope With Several QT-Prolonging Medicines
JT-CR-226 · Brain and neurologic health

Series

Syncope With Several QT-Prolonging Medicines

Recognition of drug-related long QT and torsades after syncope, with ECG verification, interaction review, electrolyte correction, and monitoring.

syncopeQT prolongationtorsades de pointes
Read An Isolated Prolonged aPTT Before Surgery
JT-CR-227 · Cancer, blood, infection, and immunity

Series

An Isolated Prolonged aPTT Before Surgery

A preoperative aPTT analysis using repeat sampling, bleeding history, mixing studies, heparin checks, factor assays, and procedure-specific risk.

prolonged aPTTmixing studylupus anticoagulant
Read Bilateral Hilar Adenopathy and Breathlessness
JT-CR-228 · Cancer, blood, infection, and immunity

Series

Bilateral Hilar Adenopathy and Breathlessness

Diagnostic reasoning for bilateral hilar adenopathy with dyspnea, separating sarcoidosis from infection, malignancy, exposure, and cardiac disease.

hilar adenopathysarcoidosistuberculosis
Read Severe Home Blood Pressures From the Wrong Cuff Size
JT-CR-229 · Heart and vascular care

Series

Severe Home Blood Pressures From the Wrong Cuff Size

Measurement-safety reasoning for severe home blood pressure values caused by an undersized cuff, without missing true hypertensive emergencies.

home blood pressurecuff sizehypertension
Read Tongue Swelling During ACE-Inhibitor Therapy
JT-CR-230 · Medicines and care safety

Series

Tongue Swelling During ACE-Inhibitor Therapy

Airway-first reasoning for ACE-inhibitor angioedema, distinguishing bradykinin swelling from anaphylaxis and preventing unsafe rechallenge.

angioedemaACE inhibitorairway
Read Resting Bradycardia in a Competitive Athlete
JT-CR-231 · Musculoskeletal, sports, and rehabilitation

Series

Resting Bradycardia in a Competitive Athlete

Risk calibration for athletic bradycardia, distinguishing physiologic adaptation from conduction disease, energy deficiency, and myocarditis.

athlete bradycardiasports cardiologyconduction disease
Read Chronic Pelvic Pain With Normal Initial Imaging
JT-CR-232 · Reproductive and postpartum care

Series

Chronic Pelvic Pain With Normal Initial Imaging

Longitudinal reasoning for chronic pelvic pain after normal imaging, integrating endometriosis, pelvic floor, bladder and bowel causes, and trauma-aware care.

chronic pelvic painendometriosispelvic floor
Read A Child Swallows a Button Battery
JT-CR-233 · Children and adolescent health

Series

A Child Swallows a Button Battery

Time-critical management of button-battery ingestion, including immediate imaging, esophageal removal, mitigation, delayed injury, and prevention.

button batteryforeign body ingestionpediatric emergency
Read Enlarging Hands, Headache, and New Diabetes
JT-CR-234 · Brain and neurologic health

Series

Enlarging Hands, Headache, and New Diabetes

Diagnostic reasoning for acromegaly, using IGF-1, glucose-suppressed growth hormone, pituitary imaging, visual assessment, and comorbidity care.

acromegalyIGF-1pituitary adenoma
Read An Animal Bite With Uncertain Vaccination History
JT-CR-235 · Cancer, blood, infection, and immunity

Series

An Animal Bite With Uncertain Vaccination History

A bite assessment integrating wound injury, infection, tetanus protection, rabies risk, animal observation, public health, and access.

animal biterabies prophylaxistetanus
Read Gait Change, Urinary Urgency, and Cognitive Slowing
JT-CR-236 · Men's health and urology

Series

Gait Change, Urinary Urgency, and Cognitive Slowing

A normal-pressure hydrocephalus analysis using objective gait testing, brain imaging, drainage response, mimic review, and shunt-risk counseling.

normal pressure hydrocephalusgait disorderurinary urgency
Read Low Milk Supply and Poor Infant Weight Gain
JT-CR-237 · Children and adolescent health

Series

Low Milk Supply and Poor Infant Weight Gain

A paired feeding assessment for low milk supply and poor growth, distinguishing milk production, transfer, infant illness, and supplementation needs.

low milk supplyinfant weight gainmilk transfer
Read Atraumatic Hip Pain After Repeated Steroid Exposure
JT-CR-238 · Musculoskeletal, sports, and rehabilitation

Series

Atraumatic Hip Pain After Repeated Steroid Exposure

Early recognition of femoral-head osteonecrosis after cumulative steroid use, including MRI, collapse risk, infection exclusion, and joint preservation.

osteonecrosiship painglucocorticoids
Read Insomnia in a Rotating-Shift Worker
JT-CR-239 · Lung and sleep health

Series

Insomnia in a Rotating-Shift Worker

A circadian and occupational analysis of rotating-shift insomnia, sleepiness, drowsy-driving risk, schedule design, and adapted insomnia care.

shift work disorderinsomniacircadian rhythm
Read A Chronic Lower-Leg Ulcer
JT-CR-240 · Brain and neurologic health

Series

A Chronic Lower-Leg Ulcer

A mechanism-based leg-ulcer assessment covering venous and arterial disease, neuropathy, infection, atypical wounds, compression, and healing.

leg ulcervenous diseaseperipheral artery disease
Read Weight Loss, Weakness, and Poor Dentition in Later Life
JT-CR-241 · Aging and palliative care

Series

Weight Loss, Weakness, and Poor Dentition in Later Life

A geriatric malnutrition analysis linking oral disease, swallowing, chronic illness, mood, medicines, food access, refeeding risk, and recovery.

unintentional weight lossmalnutritionoral health
Read Hyperthermia and Rigidity After Medication Changes
JT-CR-242 · Mental, behavioral, and substance-use health

Series

Hyperthermia and Rigidity After Medication Changes

Emergency differentiation of neuroleptic malignant syndrome, serotonin toxicity, malignant catatonia, heat illness, and other hypermetabolic crises.

hyperthermiarigidityneuroleptic malignant syndrome
Read Pallor, Oliguria, and Thrombocytopenia After Bloody Diarrhea
JT-CR-243 · Children and adolescent health

Series

Pallor, Oliguria, and Thrombocytopenia After Bloody Diarrhea

Clinical reasoning for suspected hemolytic uremic syndrome after bloody diarrhea, with renal, neurologic, and hematologic risk assessment.

hemolytic uremic syndromebloody diarrheaacute kidney injury